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Abstract

Review Article

The Gut-Brain Axis: Exploring the Bidirectional Communication Between the Gut Microbiome and the Brain

Bhoomi Aggarwal*

Published: 27 September, 2024 | Volume 8 - Issue 1 | Pages: 047-057

The gut microbiome is a complex network of interactions between the brain and the gastrointestinal tract, playing a pivotal role in human health and disease. The microbiota-gut-brain axis (GBA) serves as a crucial connector between the brain’s emotional and cognitive centers and the peripheral intestinal functions, emphasizing the profound impact of gut health on overall well-being. The GBA is characterized by a symbiotic relationship between the gut and the brain, regulating the expression of inflammatory cytokines and neurotransmitters. The MGBA is also regulated by microbial metabolites, such as short-chain fatty acids (SCFAs) and fatty acid derivatives. This paper focuses on the importance of the GBA in regulating gut health and the potential for targeted therapeutic interventions to improve health outcomes. The implications of this research are vast, suggesting that future strategies aimed at modulating the gut biome may offer promising avenues for the development of personalized medicine and dietary interventions.

Read Full Article HTML DOI: 10.29328/journal.jfsr.1001064 Cite this Article Read Full Article PDF

Keywords:

Gut-Brain Axis, Gut Microbiome, Enteric Nervous System, Gut Hormones, Neurological Disorder

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University of Agriculture, Pakistan

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Assaf Harofeh Medical Center, Israel

Leonid Feldman

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Dr. Shuaib Kayode Aremu

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Ekiti State University, Nigeria

Adebukola Ajite

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Wollo University, Ethiopia

Atsedemariam Andualem

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Palestine College of Nursing, Khan Younis, Gaza Strip, Palestine

Ayman M Abu Mustafa

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